Cell viability was assessed 3 days after treatment with FOXO4-DRI at 0, 12.5, 25, 50, and 100 M, respectively, using the Cell Counting Kit-8 (CCK-8) Assay (Dojindo, Rockville, MD, United States)
Caspase-3 (cysteinyl aspartate-specific proteinase-3) is an important proteolytic enzyme responsible for the execution of apoptosis
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Severe kidney impairment Limited data
Kahler, W., Kuklinski, B., Ruhlmann, C., and Plotz, C